While routine cleaning agents and biocides play a vital role in cleanroom cleaning and disinfection, they’re not always enough on their own.
This is because certain bacteria and fungi can form spores; highly resistant structures capable of surviving extreme environmental conditions. To effectively eliminate these organisms, a specialised solution is required: a sporicide.
Sporicides are highly effective at destroying spores, but they can come with challenges. Many have limited shelf lives due to chemical instability once activated, and some formulations may be corrosive or harsh on sensitive equipment.
As a result, selecting the right sporicide is critical for maintaining both cleanliness and operational integrity within controlled environments.
What is Zyceine?
Zyceine is an award-winning sporicide, unique from AGMA, that combines convenience with efficacy, safety and a longer shelf life than other sporicides.
It has been designed to combine high-performance disinfection with ease of use, safety, and improved stability compared to many conventional products.
A key innovation behind Zyceine is the 2-part pouch system. This design keeps active ingredients separated until the point of use, preventing premature degradation and maintaining product stability. The components are mixed by breaking the seal and waiting 5 minutes for the solution to homogenise – the product is then activated and ready to disinfect.
For wipe applications, the solution should be thoroughly manipulated to ensure complete homogenisation. For liquid use, full activation typically occurs within approximately five minutes, after which the solution is ready for use in mopping systems or for impregnating dry wipes.
For smaller applications, the 200ml format is ideal. However, larger surface areas may require repeated mixing cycles to prepare sufficient solution. To address this, the 1L format allows for coverage of up to five times the surface area without additional waiting time, while maintaining the same level of efficacy.
For added convenience, pre-impregnated sterile Zyceine wipes in WFI-quality materials are also available for use across a range of surfaces.
Key benefits of Zyceine
- Trusted and widely used across multiple NHS trusts and pharmaceutical manufacturing environments
- Leaves minimal residue after application
- Effective against a broad spectrum of microorganisms, including bacteria, fungi, and spores
- Offers an extended unopened shelf life of up to two years, helping to preserve product efficacy over time
Criteria | AGMA Zyceine |
| Biocidal Activity/Micro Efficacy (bacteria, fungi, viruses, spores) | Highly effective, fast acting broad-spectrum biocide with extensive independent EN testing and validation of proven efficacy against bacteria, viruses, fungi, moulds, yeasts and spores. (* see Micro Efficacy Data sheet for comprehensive details) |
| Shelf life (unopened) | 2 years (unopened) shelf-life and once activated an 8-hour window of validated ‘in use’ efficacy. Unique pack format takes up less storage space & creates less plastic for disposal than your traditional packaging generated by use of other pack/delivery systems. Irradiated as one unit and activated in the pouch. |
| Application | Fast acting: Unique (award-winning) duo pack pouch is activated by simply rolling down the pouch, to break the internal seal allowing contents to mix then stand to fully activate before use. Pre wetted wipe pack avoids necessity for trigger spray & dry wipes. This guarantees solution loading on each wipe. (* See Micro efficacy TDS for detailed contact times) |
| Compliance with EU GMP Annex 1 (practical use / claims / residue) | Aids tight bioburden control in aseptic areas where packaging & traceability must support clean transfer & audit ready SOP’s meeting Annex -1 requirements for use of a validated sterile sporicide. Gamma-irradiated sterile pouches. Primarily for use in Grade A/B environments |
| Health & Safety | Easy to handle, activate and dispense Non-hazardous for transport. Increased operator safety on activation due to unique closed pack system developed to activate the product on site at point of use. Less chance of spillage & aerosolization. Wipes= known quantity of solution per wipe, repeatable, constant and avoids waste by overspray. Does not corrode delicate surfaces when applied as per AGMA guidelines. (* see TDS for more information) |
| PPE | PPE: while it is less aggressive than some alternatives, it is still a chemical agent. PPE, should include skin/body, eye, footwear & respiratory protection. |
| Stability (storage / in-use stability) | Totally stable until activated – Activated pack has an 8-hour efficacy. Fluid and wipe formats created for cleanrooms. |
Download the Zyceine Technical Datasheet here: https://agma.co.uk/product/sterile-zyceine-in-wfi-1l-liquid-pouch/
Final thoughts
Sporicides play a crucial role in maintaining sterility within cleanroom environments.
Zyceine delivers a high level of performance while addressing limitations found in some sporicidal products, including stability, usability, and material compatibility.
If you would like more information or to place an order, please get in touch.
